Influence of vaccination with the immunocomplex vaccine from the VNIVIP strain on IL-6 gene expression and representation of opportunitical microorganisms in the intestine of laying hen

The immunocomplex vaccine against infectious bursal disease from the VNIVIP strain has strong immunogenic properties, including active expression of IL-6 cytokine synthesis genes in tissues bursa Fabricius and cecum. This phenomenon stimulates a local non-specific immune response, resulting reduction representation pathogenic opportunistic microorganisms intestines chickens. As result studies, it was found that relative caecum chickens Loman White cross reached 2.7-fold excess over control level, bag - 15.6-fold level. content bacteria Escherichia coli group, as sanitary indicative microorganisms, decreased by 4 times under influence (from 0.253% group to 0.064% vaccinated group). variety staphylococci also reduced, only unidentifiable representatives genus Staphylococcus were group.